BDBM50430436 CHEMBL2335070

SMILES: Oc1ccc2nc(-c3ccc4ccccc4c3)n(-c3ccnc(NC4CCCCC4)n3)c2c1

InChI Key: InChIKey=NDZUGGRYLOMQOG-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50430436 (CHEMBL2335070) Show SMILES Oc1ccc2nc(-c3ccc4ccccc4c3)n(-c3ccnc(NC4CCCCC4)n3)c2c1 Show InChI InChI=1S/C27H25N5O/c33-22-12-13-23-24(17-22)32(25-14-15-28-27(31-25)29-21-8-2-1-3-9-21)26(30-23)20-11-10-18-6-4-5-7-19(18)16-20/h4-7,10-17,21,33H,1-3,8-9H2,(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.17E+4	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6X-tagged human recombinant JNK3 catalytic domain expressed in Escherichia coli BL21 (DE3) by surface plasmon reson...				Bioorg Med Chem 21: 2271-85 (2013) Article DOI: 10.1016/j.bmc.2013.02.021 BindingDB Entry DOI: 10.7270/Q29W0GVC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50430436 (CHEMBL2335070) Show SMILES Oc1ccc2nc(-c3ccc4ccccc4c3)n(-c3ccnc(NC4CCCCC4)n3)c2c1 Show InChI InChI=1S/C27H25N5O/c33-22-12-13-23-24(17-22)32(25-14-15-28-27(31-25)29-21-8-2-1-3-9-21)26(30-23)20-11-10-18-6-4-5-7-19(18)16-20/h4-7,10-17,21,33H,1-3,8-9H2,(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.17E+4	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Binding affinity to JNK3 (unknown origin) by surface plasmon resonance analysis in presence of ATP				Bioorg Med Chem Lett 23: 1639-42 (2013) Article DOI: 10.1016/j.bmcl.2013.01.082 BindingDB Entry DOI: 10.7270/Q2F76DXD
					More data for this Ligand-Target Pair