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BDBM50430687 CHEMBL2333508

SMILES: COc1ccc(COC(=O)C2[C@@H](NC(=O)N=C2C)c2ccco2)cc1

InChI Key: InChIKey=LWUUGEWVWDDKTP-LYKKTTPLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430687   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/iodide cotransporter


(Rattus norvegicus)		BDBM50430687
PNG
(CHEMBL2333508)
Show SMILES COc1ccc(COC(=O)C2[C@@H](NC(=O)N=C2C)c2ccco2)cc1 |r,c:15|
Show InChI InChI=1S/C18H18N2O5/c1-11-15(16(20-18(22)19-11)14-4-3-9-24-14)17(21)25-10-12-5-7-13(23-2)8-6-12/h3-9,15-16H,10H2,1-2H3,(H,20,22)/t15?,16-/m0/s1
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Similars
Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay

Eur J Med Chem 62: 722-7 (2013)


Article DOI: 10.1016/j.ejmech.2013.01.043
BindingDB Entry DOI: 10.7270/Q2MS3V4D
More data for this
Ligand-Target Pair