BDBM50431018 CHEMBL2338326

SMILES: OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc2ccccc2c1

InChI Key: InChIKey=NTFMWXJMENAQDA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50431018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50431018 (CHEMBL2338326) Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc2ccccc2c1 Show InChI InChI=1S/C18H14N2O4/c21-15-8-14(9-19-17(15)18(24)20-10-16(22)23)13-6-5-11-3-1-2-4-12(11)7-13/h1-9,21H,10H2,(H,20,24)(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Inhibition of full length human recombinant EGLN-3 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysis				J Med Chem 56: 9369-402 (2014) Article DOI: 10.1021/jm400386j BindingDB Entry DOI: 10.7270/Q290258T
					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM50431018 (CHEMBL2338326) Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc2ccccc2c1 Show InChI InChI=1S/C18H14N2O4/c21-15-8-14(9-19-17(15)18(24)20-10-16(22)23)13-6-5-11-3-1-2-4-12(11)7-13/h1-9,21H,10H2,(H,20,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...				J Med Chem 56: 3680-8 (2013) Article DOI: 10.1021/jm400193d BindingDB Entry DOI: 10.7270/Q21V5GBQ
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50431018 (CHEMBL2338326) Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc2ccccc2c1 Show InChI InChI=1S/C18H14N2O4/c21-15-8-14(9-19-17(15)18(24)20-10-16(22)23)13-6-5-11-3-1-2-4-12(11)7-13/h1-9,21H,10H2,(H,20,24)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant EGLN-1 using DLDLEALAPYIPADDDFQL as substrate after 20 mins by mass spectrophotometric analysis				J Med Chem 56: 9369-402 (2014) Article DOI: 10.1021/jm400386j BindingDB Entry DOI: 10.7270/Q290258T
					More data for this Ligand-Target Pair