BDBM50431162 CHEMBL2332062

SMILES: COc1cccc(CN(CCN(C)C)C(=O)Nc2ccc(cc2OCCN(C)C)-c2cn[nH]c2)c1

InChI Key: InChIKey=WSHAJIVCJZGUKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50431162 (CHEMBL2332062) Show SMILES COc1cccc(CN(CCN(C)C)C(=O)Nc2ccc(cc2OCCN(C)C)-c2cn[nH]c2)c1 Show InChI InChI=1S/C26H36N6O3/c1-30(2)11-12-32(19-20-7-6-8-23(15-20)34-5)26(33)29-24-10-9-21(22-17-27-28-18-22)16-25(24)35-14-13-31(3)4/h6-10,15-18H,11-14,19H2,1-5H3,(H,27,28)(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) after 4 hrs by HTRF assay				J Med Chem 56: 3568-81 (2013) Article DOI: 10.1021/jm400062r BindingDB Entry DOI: 10.7270/Q28C9XMJ
					More data for this Ligand-Target Pair