BDBM50431788 CHEMBL2346929
SMILES: CC#CCn1c(nc2ccn(Cc3ccc4cc(F)ccc4n3)c2c1=O)N1CCC[C@@H](N)C1
InChI Key: InChIKey=WOJQMSFYRUGCKE-LJQANCHMSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50431788 (CHEMBL2346929) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Science Curated by ChEMBL | Assay Description Inhibition of human DPP4 using Gly-Pro-AMC as substrate treated with enzyme 10 mins prior to substrate addition measured after 10 mins | Bioorg Med Chem 21: 1749-55 (2013) Article DOI: 10.1016/j.bmc.2013.01.062 BindingDB Entry DOI: 10.7270/Q2R78GMR | |||||||||||
More data for this Ligand-Target Pair |