BDBM50431907 CHEMBL2347808

SMILES: CC(C)Nc1c(cnc2ccccc12)C#N

InChI Key: InChIKey=VSBHCSZZUBGNFZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM50431907 (CHEMBL2347808) Show SMILES CC(C)Nc1c(cnc2ccccc12)C#N Show InChI InChI=1S/C13H13N3/c1-9(2)16-13-10(7-14)8-15-12-6-4-3-5-11(12)13/h3-6,8-9H,1-2H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of wild type GST-tagged LRRK2 (970-2527 amino acids)(unknown origin) assessed as inhibition of LRRKtide phosphorylation by HTRF assay				Bioorg Med Chem Lett 23: 1974-7 (2013) Article DOI: 10.1016/j.bmcl.2013.02.041 BindingDB Entry DOI: 10.7270/Q2FQ9XZ1
					More data for this Ligand-Target Pair