BDBM50432011 CHEMBL2348732
SMILES: CC(=O)Nc1n[nH]c(=O)cc1-c1ccccc1
InChI Key: InChIKey=SZFFFKYNIZCDRA-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human)) | BDBM50432011 (CHEMBL2348732) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Strasbourg Curated by ChEMBL | Assay Description Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP | Bioorg Med Chem Lett 23: 2007-13 (2013) Article DOI: 10.1016/j.bmcl.2013.02.027 BindingDB Entry DOI: 10.7270/Q2T1551T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT) | BDBM50432011 (CHEMBL2348732) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Strasbourg Curated by ChEMBL | Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an... | Bioorg Med Chem Lett 23: 2007-13 (2013) Article DOI: 10.1016/j.bmcl.2013.02.027 BindingDB Entry DOI: 10.7270/Q2T1551T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha (Sus scrofa) | BDBM50432011 (CHEMBL2348732) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Strasbourg Curated by ChEMBL | Assay Description Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP | Bioorg Med Chem Lett 23: 2007-13 (2013) Article DOI: 10.1016/j.bmcl.2013.02.027 BindingDB Entry DOI: 10.7270/Q2T1551T | |||||||||||
More data for this Ligand-Target Pair |