BDBM50432055 CHEMBL2348954

SMILES: FC(F)(F)c1cccc(Sc2ccc3nnc(-c4cccc(c4)N4CCNCC4)n3n2)c1

InChI Key: InChIKey=PKGPUOBBFPSVPX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM50432055 (CHEMBL2348954) Show SMILES FC(F)(F)c1cccc(Sc2ccc3nnc(-c4cccc(c4)N4CCNCC4)n3n2)c1 Show InChI InChI=1S/C22H19F3N6S/c23-22(24,25)16-4-2-6-18(14-16)32-20-8-7-19-27-28-21(31(19)29-20)15-3-1-5-17(13-15)30-11-9-26-10-12-30/h1-8,13-14,26H,9-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of wild type LRRK2 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 23: 1967-73 (2013) Article DOI: 10.1016/j.bmcl.2013.02.043 BindingDB Entry DOI: 10.7270/Q2P84D8N
					More data for this Ligand-Target Pair