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SMILES: Nc1nccc(n1)-n1cc(-c2cccnc2Cl)c2cnc(Cl)cc12

InChI Key: InChIKey=UNLYRICJXHKLFW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50432335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50432335 (CHEMBL2348152) Show SMILES Nc1nccc(n1)-n1cc(-c2cccnc2Cl)c2cnc(Cl)cc12 Show InChI InChI=1S/C16H10Cl2N6/c17-13-6-12-10(7-22-13)11(9-2-1-4-20-15(9)18)8-24(12)14-3-5-21-16(19)23-14/h1-8H,(H2,19,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CDC7 in human HCT116 cells assessed as MCM2 phosphorylation				Bioorg Med Chem Lett 23: 2056-60 (2013) Article DOI: 10.1016/j.bmcl.2013.02.007 BindingDB Entry DOI: 10.7270/Q23B61HD
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50432335 (CHEMBL2348152) Show SMILES Nc1nccc(n1)-n1cc(-c2cccnc2Cl)c2cnc(Cl)cc12 Show InChI InChI=1S/C16H10Cl2N6/c17-13-6-12-10(7-22-13)11(9-2-1-4-20-15(9)18)8-24(12)14-3-5-21-16(19)23-14/h1-8H,(H2,19,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CDC7 (unknown origin)				Bioorg Med Chem Lett 23: 2056-60 (2013) Article DOI: 10.1016/j.bmcl.2013.02.007 BindingDB Entry DOI: 10.7270/Q23B61HD
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50432335 (CHEMBL2348152) Show SMILES Nc1nccc(n1)-n1cc(-c2cccnc2Cl)c2cnc(Cl)cc12 Show InChI InChI=1S/C16H10Cl2N6/c17-13-6-12-10(7-22-13)11(9-2-1-4-20-15(9)18)8-24(12)14-3-5-21-16(19)23-14/h1-8H,(H2,19,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2 (unknown origin)				Bioorg Med Chem Lett 23: 2056-60 (2013) Article DOI: 10.1016/j.bmcl.2013.02.007 BindingDB Entry DOI: 10.7270/Q23B61HD
					More data for this Ligand-Target Pair