BDBM50432411 CHEMBL2349001

SMILES: O=C(Nc1cn2nc(Oc3cccc(NC(=O)c4ccno4)c3)ccc2n1)C1CC1

InChI Key: InChIKey=RGZLIVANFAQNFW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50432411 (CHEMBL2349001) Show SMILES O=C(Nc1cn2nc(Oc3cccc(NC(=O)c4ccno4)c3)ccc2n1)C1CC1 Show InChI InChI=1S/C20H16N6O4/c27-19(12-4-5-12)24-16-11-26-17(23-16)6-7-18(25-26)29-14-3-1-2-13(10-14)22-20(28)15-8-9-21-30-15/h1-3,6-12H,4-5H2,(H,22,28)(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using biotinylated poly(Glu:Tyr) as substrate after 5 mins by AlphaScreen assay in presence of 10 uM of ATP				Bioorg Med Chem 21: 2333-45 (2013) Article DOI: 10.1016/j.bmc.2013.01.074 BindingDB Entry DOI: 10.7270/Q22B90C1
					More data for this Ligand-Target Pair