BDBM50432581 CHEMBL2347030
SMILES: NCCCc1c[nH]c2c(F)cccc12
InChI Key: InChIKey=OOYDQQMBWSRGBX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432581 (CHEMBL2347030) | PDB KEGG DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (MPO) (Homo sapiens (Human)) | BDBM50432581 (CHEMBL2347030) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (MPO) (Homo sapiens (Human)) | BDBM50432581 (CHEMBL2347030) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair |