BDBM50432589 CHEMBL2347182

SMILES: NC(=O)CCc1c[nH]c2c(F)cccc12

InChI Key: InChIKey=ITOJDOQGJOJVRM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50432589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myeloperoxidase (MPO) (Homo sapiens (Human))	BDBM50432589 (CHEMBL2347182) Show SMILES NC(=O)CCc1c[nH]c2c(F)cccc12 Show InChI InChI=1S/C11H11FN2O/c12-9-3-1-2-8-7(4-5-10(13)15)6-14-11(8)9/h1-3,6,14H,4-5H2,(H2,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	271	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay				J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T
					More data for this Ligand-Target Pair
Myeloperoxidase (MPO) (Homo sapiens (Human))	BDBM50432589 (CHEMBL2347182) Show SMILES NC(=O)CCc1c[nH]c2c(F)cccc12 Show InChI InChI=1S/C11H11FN2O/c12-9-3-1-2-8-7(4-5-10(13)15)6-14-11(8)9/h1-3,6,14H,4-5H2,(H2,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA				J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T
					More data for this Ligand-Target Pair