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BDBM50432682 CHEMBL2347959

SMILES: CC(C)CCCC(=O)Nc1cccc(c1)-c1c(oc2ncnc(N[C@H](CO)c3ccccc3)c12)-c1ccccc1

InChI Key: InChIKey=UBBSUOQHUJQYIS-HHHXNRCGSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432682   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50432682
PNG
(CHEMBL2347959)
Show SMILES CC(C)CCCC(=O)Nc1cccc(c1)-c1c(oc2ncnc(N[C@H](CO)c3ccccc3)c12)-c1ccccc1 |r|
Show InChI InChI=1S/C33H34N4O3/c1-22(2)11-9-18-28(39)36-26-17-10-16-25(19-26)29-30-32(37-27(20-38)23-12-5-3-6-13-23)34-21-35-33(30)40-31(29)24-14-7-4-8-15-24/h3-8,10,12-17,19,21-22,27,38H,9,11,18,20H2,1-2H3,(H,36,39)(H,34,35,37)/t27-/m1/s1
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KEGG

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PC cid
PC sid
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Similars
Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human wild type GST-tagged EGFR kinase domain expressed in Sf9 cells by luminescence assay

J Med Chem 56: 3889-903 (2013)


Article DOI: 10.1021/jm400072p
BindingDB Entry DOI: 10.7270/Q27W6DJ5
More data for this
Ligand-Target Pair