null
SMILES: CC(=O)Nc1cccc(c1)-c1c(oc2ncnc(N[C@H](CO)c3ccccc3)c12)-c1ccccc1
InChI Key: InChIKey=QTVUEQZXBRDKNW-HSZRJFAPSA-N
PDB links: 1 PDB ID matches this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50432688 (CHEMBL2347965) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a |
National Health Research Institutes Curated by ChEMBL | Assay Description Inhibition of human wild type GST-tagged EGFR kinase domain expressed in Sf9 cells by luminescence assay | J Med Chem 56: 3889-903 (2013) Article DOI: 10.1021/jm400072p BindingDB Entry DOI: 10.7270/Q27W6DJ5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |