BDBM50432691 CHEMBL2347967

SMILES: OC[C@@H](Nc1ncnc2oc(c(-c3cccc(c3)[N+]([O-])=O)c12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=VBHDQDBZRZFSML-OAQYLSRUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50432691 (CHEMBL2347967) Show SMILES OC[C@@H](Nc1ncnc2oc(c(-c3cccc(c3)[N+]([O-])=O)c12)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H20N4O4/c31-15-21(17-8-3-1-4-9-17)29-25-23-22(19-12-7-13-20(14-19)30(32)33)24(18-10-5-2-6-11-18)34-26(23)28-16-27-25/h1-14,16,21,31H,15H2,(H,27,28,29)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human wild type GST-tagged EGFR kinase domain expressed in Sf9 cells by luminescence assay				J Med Chem 56: 3889-903 (2013) Article DOI: 10.1021/jm400072p BindingDB Entry DOI: 10.7270/Q27W6DJ5
					More data for this Ligand-Target Pair