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SMILES: OC[C@@H](Nc1ncnc2oc(c(-c3ccco3)c12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=SNPLCMYCBIYMEV-GOSISDBHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432694   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50432694
PNG
(CHEMBL2347970)
Show SMILES OC[C@@H](Nc1ncnc2oc(c(-c3ccco3)c12)-c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C24H19N3O3/c28-14-18(16-8-3-1-4-9-16)27-23-21-20(19-12-7-13-29-19)22(17-10-5-2-6-11-17)30-24(21)26-15-25-23/h1-13,15,18,28H,14H2,(H,25,26,27)/t18-/m1/s1
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n/an/a 434n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human wild type GST-tagged EGFR kinase domain expressed in Sf9 cells by luminescence assay

J Med Chem 56: 3889-903 (2013)


Article DOI: 10.1021/jm400072p
BindingDB Entry DOI: 10.7270/Q27W6DJ5
More data for this
Ligand-Target Pair