BDBM50432698 CHEMBL2347974

SMILES: CC[C@@H](Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=FRCSDAZKXTYDMZ-JOCHJYFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50432698 (CHEMBL2347974) Show SMILES CC[C@@H](Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C27H23N3O/c1-2-22(19-12-6-3-7-13-19)30-26-24-23(20-14-8-4-9-15-20)25(21-16-10-5-11-17-21)31-27(24)29-18-28-26/h3-18,22H,2H2,1H3,(H,28,29,30)/t22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human wild type GST-tagged EGFR kinase domain expressed in Sf9 cells by luminescence assay				J Med Chem 56: 3889-903 (2013) Article DOI: 10.1021/jm400072p BindingDB Entry DOI: 10.7270/Q27W6DJ5
					More data for this Ligand-Target Pair