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SMILES: C[C@@H](Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=GEVOOZNHXCBXLI-GOSISDBHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432699   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50432699
PNG
(CHEMBL2348194)
Show SMILES C[C@@H](Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C26H21N3O/c1-18(19-11-5-2-6-12-19)29-25-23-22(20-13-7-3-8-14-20)24(21-15-9-4-10-16-21)30-26(23)28-17-27-25/h2-18H,1H3,(H,27,28,29)/t18-/m1/s1
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MMDB

KEGG

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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 2.99E+3n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human wild type GST-tagged EGFR kinase domain expressed in Sf9 cells by luminescence assay

J Med Chem 56: 3889-903 (2013)


Article DOI: 10.1021/jm400072p
BindingDB Entry DOI: 10.7270/Q27W6DJ5
More data for this
Ligand-Target Pair