BDBM50432919 CHEMBL2376856

SMILES: O=C(N1CCCCC1)n1nnnc1Cc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=DUPKAESIJQIEMA-UHFFFAOYSA-N

Data: 4 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50432919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50432919 (CHEMBL2376856) Show SMILES O=C(N1CCCCC1)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H21N5O/c26-20(24-13-5-2-6-14-24)25-19(21-22-23-25)15-16-9-11-18(12-10-16)17-7-3-1-4-8-17/h1,3-4,7-12H,2,5-6,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of MAGL (unknown origin) expressed in African green monkey COS7 cell cytosolic fraction assessed as [3H]2-AG hydrolysis to [3H]arachidonic...				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50432919 (CHEMBL2376856) Show SMILES O=C(N1CCCCC1)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H21N5O/c26-20(24-13-5-2-6-14-24)25-19(21-22-23-25)15-16-9-11-18(12-10-16)17-7-3-1-4-8-17/h1,3-4,7-12H,2,5-6,13-15H2	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50432919 (CHEMBL2376856) Show SMILES O=C(N1CCCCC1)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H21N5O/c26-20(24-13-5-2-6-14-24)25-19(21-22-23-25)15-16-9-11-18(12-10-16)17-7-3-1-4-8-17/h1,3-4,7-12H,2,5-6,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Agonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric an...				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50432919 (CHEMBL2376856) Show SMILES O=C(N1CCCCC1)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H21N5O/c26-20(24-13-5-2-6-14-24)25-19(21-22-23-25)15-16-9-11-18(12-10-16)17-7-3-1-4-8-17/h1,3-4,7-12H,2,5-6,13-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric anal...				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50432919 (CHEMBL2376856) Show SMILES O=C(N1CCCCC1)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H21N5O/c26-20(24-13-5-2-6-14-24)25-19(21-22-23-25)15-16-9-11-18(12-10-16)17-7-3-1-4-8-17/h1,3-4,7-12H,2,5-6,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ elevation incuba...				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50432919 (CHEMBL2376856) Show SMILES O=C(N1CCCCC1)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H21N5O/c26-20(24-13-5-2-6-14-24)25-19(21-22-23-25)15-16-9-11-18(12-10-16)17-7-3-1-4-8-17/h1,3-4,7-12H,2,5-6,13-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Antagonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced intracellular Ca2+ elevati...				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair