BDBM50432927 CHEMBL2377219

SMILES: O=S(=O)(Nc1ccccn1)c1ccc(cc1)-c1ccc(cc1)C#N

InChI Key: InChIKey=DEJLPRSKSNGMCR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50432927 (CHEMBL2377219) Show SMILES O=S(=O)(Nc1ccccn1)c1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C18H13N3O2S/c19-13-14-4-6-15(7-5-14)16-8-10-17(11-9-16)24(22,23)21-18-3-1-2-12-20-18/h1-12H,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	604	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human HEK293 cells				Bioorg Med Chem Lett 23: 2344-8 (2013) Article DOI: 10.1016/j.bmcl.2013.02.066 BindingDB Entry DOI: 10.7270/Q29P3314
					More data for this Ligand-Target Pair