BDBM50432936 CHEMBL2377209

SMILES: O=S(=O)(Nc1ccc2ccccc2n1)c1ccc(cc1)-c1ccc(cc1)C#N

InChI Key: InChIKey=BLNIEDYQLOQOTI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50432936 (CHEMBL2377209) Show SMILES O=S(=O)(Nc1ccc2ccccc2n1)c1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H15N3O2S/c23-15-16-5-7-17(8-6-16)18-9-12-20(13-10-18)28(26,27)25-22-14-11-19-3-1-2-4-21(19)24-22/h1-14H,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human HEK293 cells				Bioorg Med Chem Lett 23: 2344-8 (2013) Article DOI: 10.1016/j.bmcl.2013.02.066 BindingDB Entry DOI: 10.7270/Q29P3314
					More data for this Ligand-Target Pair