BDBM50432938 CHEMBL2377207

SMILES: Cc1ccc(F)c(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C#N)n1

InChI Key: InChIKey=ZHKFLSRNLYZTFV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50432938 (CHEMBL2377207) Show SMILES Cc1ccc(F)c(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C#N)n1 Show InChI InChI=1S/C19H14FN3O2S/c1-13-2-11-18(20)19(22-13)23-26(24,25)17-9-7-16(8-10-17)15-5-3-14(12-21)4-6-15/h2-11H,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human HEK293 cells				Bioorg Med Chem Lett 23: 2344-8 (2013) Article DOI: 10.1016/j.bmcl.2013.02.066 BindingDB Entry DOI: 10.7270/Q29P3314
					More data for this Ligand-Target Pair