null

SMILES: C[C@@]1(COC(=O)c2ccccc2)[C@H](CC[C@@]2(C)[C@H]1C[C@H](OC(=O)c1ccc(cc1)C#N)[C@@]1(C)Oc3cc(oc(=O)c3[C@H](O)[C@H]21)-c1cccnc1)OC(=O)c1ccccc1

InChI Key: InChIKey=QMBMWRWYPUYZQH-RXTJMKIFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50433201 (CHEMBL2375704) Show SMILES C[C@@]1(COC(=O)c2ccccc2)[C@H](CC[C@@]2(C)[C@H]1C[C@H](OC(=O)c1ccc(cc1)C#N)[C@@]1(C)Oc3cc(oc(=O)c3[C@H](O)[C@H]21)-c1cccnc1)OC(=O)c1ccccc1 |r| Show InChI InChI=1S/C47H42N2O10/c1-45-21-20-36(57-42(52)30-13-8-5-9-14-30)46(2,27-55-41(51)29-11-6-4-7-12-29)35(45)24-37(58-43(53)31-18-16-28(25-48)17-19-31)47(3)40(45)39(50)38-34(59-47)23-33(56-44(38)54)32-15-10-22-49-26-32/h4-19,22-23,26,35-37,39-40,50H,20-21,24,27H2,1-3H3/t35-,36+,37+,39+,40-,45+,46+,47-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Inhibition of ACAT1 (unknown origin)				Bioorg Med Chem Lett 23: 2659-62 (2013) Article DOI: 10.1016/j.bmcl.2013.02.088 BindingDB Entry DOI: 10.7270/Q20866P3
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50433201 (CHEMBL2375704) Show SMILES C[C@@]1(COC(=O)c2ccccc2)[C@H](CC[C@@]2(C)[C@H]1C[C@H](OC(=O)c1ccc(cc1)C#N)[C@@]1(C)Oc3cc(oc(=O)c3[C@H](O)[C@H]21)-c1cccnc1)OC(=O)c1ccccc1 |r| Show InChI InChI=1S/C47H42N2O10/c1-45-21-20-36(57-42(52)30-13-8-5-9-14-30)46(2,27-55-41(51)29-11-6-4-7-12-29)35(45)24-37(58-43(53)31-18-16-28(25-48)17-19-31)47(3)40(45)39(50)38-34(59-47)23-33(56-44(38)54)32-15-10-22-49-26-32/h4-19,22-23,26,35-37,39-40,50H,20-21,24,27H2,1-3H3/t35-,36+,37+,39+,40-,45+,46+,47-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Inhibition of ACAT2 (unknown origin)				Bioorg Med Chem Lett 23: 2659-62 (2013) Article DOI: 10.1016/j.bmcl.2013.02.088 BindingDB Entry DOI: 10.7270/Q20866P3
					More data for this Ligand-Target Pair