BDBM50433373 CHEMBL2375609

SMILES: CC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1

InChI Key: InChIKey=RTTRPGNGUNHCDS-MHZLTWQESA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50433373 (CHEMBL2375609) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 |r| Show InChI InChI=1S/C29H29N5O2/c1-21(35)31-27(19-22-9-3-2-4-10-22)29(36)34-17-15-33(16-18-34)28-20-26(25-13-7-8-14-30-25)32-24-12-6-5-11-23(24)28/h2-14,20,27H,15-19H2,1H3,(H,31,35)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 2 in presence of Mn2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM50433373 (CHEMBL2375609) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 |r| Show InChI InChI=1S/C29H29N5O2/c1-21(35)31-27(19-22-9-3-2-4-10-22)29(36)34-17-15-33(16-18-34)28-20-26(25-13-7-8-14-30-25)32-24-12-6-5-11-23(24)28/h2-14,20,27H,15-19H2,1H3,(H,31,35)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Mn2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM50433373 (CHEMBL2375609) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 |r| Show InChI InChI=1S/C29H29N5O2/c1-21(35)31-27(19-22-9-3-2-4-10-22)29(36)34-17-15-33(16-18-34)28-20-26(25-13-7-8-14-30-25)32-24-12-6-5-11-23(24)28/h2-14,20,27H,15-19H2,1H3,(H,31,35)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair