BDBM50433473 CHEMBL2381070

SMILES: Fc1cc(F)cc(OCCCCCNC(=O)SCc2nnc(o2)-c2ccccc2)c1

InChI Key: InChIKey=LZSHRHKOOOQWST-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50433473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50433473 (CHEMBL2381070) Show SMILES Fc1cc(F)cc(OCCCCCNC(=O)SCc2nnc(o2)-c2ccccc2)c1 Show InChI InChI=1S/C21H21F2N3O3S/c22-16-11-17(23)13-18(12-16)28-10-6-2-5-9-24-21(27)30-14-19-25-26-20(29-19)15-7-3-1-4-8-15/h1,3-4,7-8,11-13H,2,5-6,9-10,14H2,(H,24,27)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research and Development, LLC Curated by ChEMBL					Assay Description Time dependent inhibition of human EL (19 to 500) expressed in HEK293 cells using PED-A1 as substrate by spectrophotometry				Bioorg Med Chem Lett 23: 2595-7 (2013) Article DOI: 10.1016/j.bmcl.2013.02.113 BindingDB Entry DOI: 10.7270/Q24T6KQV
					More data for this Ligand-Target Pair