BDBM50433652 CHEMBL2380835
SMILES: Fc1c(cccc1C(F)(F)F)C(=O)Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1
InChI Key: InChIKey=WPASUZBJIGBQSX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50433652 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Aurora kinase A
(Homo sapiens (Human)) | BDBM50433652
(CHEMBL2380835)Show SMILES Fc1c(cccc1C(F)(F)F)C(=O)Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1 Show InChI InChI=1S/C26H16F4N4O2/c27-22-18(6-3-7-19(22)26(28,29)30)25(36)33-15-10-8-14(9-11-15)32-20-12-13-31-23-21(20)16-4-1-2-5-17(16)24(35)34-23/h1-13H,(H,33,36)(H2,31,32,34,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
EMD Serono Research Institute, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of aurora-A (unknown origin) |
Bioorg Med Chem Lett 23: 3081-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.03.008
BindingDB Entry DOI: 10.7270/Q2QN686Z |
More data for this
Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50433652
(CHEMBL2380835)Show SMILES Fc1c(cccc1C(F)(F)F)C(=O)Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1 Show InChI InChI=1S/C26H16F4N4O2/c27-22-18(6-3-7-19(22)26(28,29)30)25(36)33-15-10-8-14(9-11-15)32-20-12-13-31-23-21(20)16-4-1-2-5-17(16)24(35)34-23/h1-13H,(H,33,36)(H2,31,32,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
EMD Serono Research Institute, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of aurora-B (unknown origin) |
Bioorg Med Chem Lett 23: 3081-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.03.008
BindingDB Entry DOI: 10.7270/Q2QN686Z |
More data for this
Ligand-Target Pair | |
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