BDBM50434232 CHEMBL2385514

SMILES: OC(=O)c1cc(nc2ccc(Cl)cc12)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=NPMGPHKLPREXTE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM50434232 (CHEMBL2385514) Show SMILES OC(=O)c1cc(nc2ccc(Cl)cc12)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C22H14ClNO3/c23-15-8-11-20-18(12-15)19(22(25)26)13-21(24-20)14-6-9-17(10-7-14)27-16-4-2-1-3-5-16/h1-13H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair