BDBM50434241 CHEMBL2385913

SMILES: CCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(OCc2ccccc2)c(OC)c1

InChI Key: InChIKey=HFWBZVFHPYLBTH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-alpha (Homo sapiens (Human))	BDBM50434241 (CHEMBL2385913) Show SMILES CCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(OCc2ccccc2)c(OC)c1 |c:5| Show InChI InChI=1S/C23H26N2O5/c1-5-29-22(26)20-15(2)25(3)23(27)24-21(20)17-11-12-18(19(13-17)28-4)30-14-16-9-7-6-8-10-16/h6-13,21H,5,14H2,1-4H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.90E+4	n/a	n/a	n/a	n/a
Genfit SA Curated by ChEMBL					Assay Description Partial agonist activity at GST-fussed RORalpha (unknown origin) assessed as recruitment of TIF2-BAP protein after overnight incubation by pull down ...				ACS Med Chem Lett 4: 504-8 (2013) Article DOI: 10.1021/ml300471d BindingDB Entry DOI: 10.7270/Q22R3T1B
					More data for this Ligand-Target Pair