BDBM50434251 CHEMBL2385732

SMILES: COC(=O)C1C(NC(=O)N=C1C)c1ccc(OCc2ccccc2)c(OC)c1

InChI Key: InChIKey=VYCQJFBWIAFJKF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-alpha (Homo sapiens (Human))	BDBM50434251 (CHEMBL2385732) Show SMILES COC(=O)C1C(NC(=O)N=C1C)c1ccc(OCc2ccccc2)c(OC)c1 |c:9| Show InChI InChI=1S/C21H22N2O5/c1-13-18(20(24)27-3)19(23-21(25)22-13)15-9-10-16(17(11-15)26-2)28-12-14-7-5-4-6-8-14/h4-11,18-19H,12H2,1-3H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a
Genfit SA Curated by ChEMBL					Assay Description Partial agonist activity at GST-fussed RORalpha (unknown origin) assessed as recruitment of TIF2-BAP protein after overnight incubation by pull down ...				ACS Med Chem Lett 4: 504-8 (2013) Article DOI: 10.1021/ml300471d BindingDB Entry DOI: 10.7270/Q22R3T1B
					More data for this Ligand-Target Pair