null
SMILES: OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
InChI Key: InChIKey=KIZUBVPJNPVIIN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50434295 (CHEMBL2386353) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)... | J Med Chem 59: 4849-58 (2016) BindingDB Entry DOI: 10.7270/Q24T6M9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50434295 (CHEMBL2386353) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at FFA1 receptor (unknown origin) expressed in human 132N1 cells measured for 90 secs by Fura-2 AM dye based calcium mobilization as... | J Med Chem 59: 4849-58 (2016) BindingDB Entry DOI: 10.7270/Q24T6M9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 4 (Homo sapiens (Human)) | BDBM50434295 (CHEMBL2386353) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 933 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at C-terminal yellow fluorescent protein-fused human FFA4 receptor transfected in HEK293 cells after 5 mins by BRET assay | ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50434295 (CHEMBL2386353) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by calcium mobilization assay | ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Mus musculus) | BDBM50434295 (CHEMBL2386353) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 148 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at mouse FFA1 receptor transfected in human T-REX-293 cells measured for 74 secs by calcium mobilization assay | ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50434295 (CHEMBL2386353) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at C-terminal yellow fluorescent protein-fused human FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assay in presenc... | ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50434295 (CHEMBL2386353) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at C-terminal yellow fluorescent protein-fused human FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assay | ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50434295 (CHEMBL2386353) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by calcium mobilization assay | ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50434295 (CHEMBL2386353) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins... | J Med Chem 59: 4849-58 (2016) BindingDB Entry DOI: 10.7270/Q24T6M9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Rattus norvegicus) | BDBM50434295 (CHEMBL2386353) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 324 | n/a | n/a | n/a | n/a |
University of Southern Denmark Curated by ChEMBL | Assay Description Agonist activity at C-terminal yellow fluorescent protein-fused rat FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assay | ACS Med Chem Lett 4: 441-445 (2013) Article DOI: 10.1021/ml4000673 BindingDB Entry DOI: 10.7270/Q2F1914M | |||||||||||
More data for this Ligand-Target Pair |