BDBM50434542 CHEMBL2386179
SMILES: Cc1ccc(cc1)[B-]1([NH2+]CCO1)c1ccccc1
InChI Key: InChIKey=XWDYILWIXQYLOL-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 6 (Homo sapiens (Human)) | BDBM50434542 (CHEMBL2386179) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bern Curated by ChEMBL | Assay Description Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assay | Bioorg Med Chem 21: 3202-13 (2013) Article DOI: 10.1016/j.bmc.2013.03.037 BindingDB Entry DOI: 10.7270/Q2KK9D6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 6 (Homo sapiens (Human)) | BDBM50434542 (CHEMBL2386179) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bern Curated by ChEMBL | Assay Description Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assay | Bioorg Med Chem 21: 3202-13 (2013) Article DOI: 10.1016/j.bmc.2013.03.037 BindingDB Entry DOI: 10.7270/Q2KK9D6T | |||||||||||
More data for this Ligand-Target Pair |