BDBM50434576 CHEMBL2386406
SMILES: Fc1cccc2oc(cc(=O)c12)-c1ccc(cc1)C#N
InChI Key: InChIKey=AMARDZYZWOUIBS-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen Receptor (Homo sapiens (Human)) | BDBM50434576 (CHEMBL2386406) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Meijo University Curated by ChEMBL | Assay Description Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay | Bioorg Med Chem 21: 2968-74 (2013) Article DOI: 10.1016/j.bmc.2013.03.060 BindingDB Entry DOI: 10.7270/Q2FT8NFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen Receptor (Homo sapiens (Human)) | BDBM50434576 (CHEMBL2386406) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Meijo University Curated by ChEMBL | Assay Description Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay | Bioorg Med Chem 21: 2968-74 (2013) Article DOI: 10.1016/j.bmc.2013.03.060 BindingDB Entry DOI: 10.7270/Q2FT8NFN | |||||||||||
More data for this Ligand-Target Pair |