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SMILES: C[C@@H]1CN(Cc2ccccc2)[C@H](CCCCO[Si](C)(C)C(C)(C)C)CN1

InChI Key: InChIKey=RHCSBPWMBOFIJC-TZIWHRDSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434741   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent N-type calcium channel subunit alpha-1B


(Rattus norvegicus (Rat))		BDBM50434741
PNG
(CHEMBL2385372)
Show SMILES C[C@@H]1CN(Cc2ccccc2)[C@H](CCCCO[Si](C)(C)C(C)(C)C)CN1 |r|
Show InChI InChI=1S/C22H40N2OSi/c1-19-17-24(18-20-12-8-7-9-13-20)21(16-23-19)14-10-11-15-25-26(5,6)22(2,3)4/h7-9,12-13,19,21,23H,10-11,14-18H2,1-6H3/t19-,21-/m1/s1
PDB

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UniChem

Similars
Article
PubMed
n/an/a 4.85E+3n/an/an/an/an/an/a



University of British Columbia

Curated by ChEMBL


Assay Description
Inhibition of rat brain Cav2.2 N-type channel expressed in HEK cells after 20 mins by FLIPR assay

Bioorg Med Chem Lett 23: 3257-61 (2013)


Article DOI: 10.1016/j.bmcl.2013.03.114
BindingDB Entry DOI: 10.7270/Q21N82H2
More data for this
Ligand-Target Pair