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SMILES: COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccsc12

InChI Key: InChIKey=IYOTVZSFTHIXBA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434754   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bone morphogenetic protein 4


(Mus musculus)		BDBM50434754
PNG
(CHEMBL2385578)
Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccsc12
Show InChI InChI=1S/C20H14N4OS/c1-25-15-4-2-13(3-5-15)14-10-22-20-17(11-23-24(20)12-14)16-6-8-21-18-7-9-26-19(16)18/h2-12H,1H3
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MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 4.57E+3n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 23: 3248-52 (2013)


Article DOI: 10.1016/j.bmcl.2013.03.113
BindingDB Entry DOI: 10.7270/Q2WW7K3P
More data for this
Ligand-Target Pair