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SMILES: C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc2ccccc12

InChI Key: InChIKey=WWJXFRWWRLRVCD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434755   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bone morphogenetic protein 4


(Mus musculus)		BDBM50434755
PNG
(CHEMBL2385592)
Show SMILES C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc2ccccc12
Show InChI InChI=1S/C24H21N5S/c1-2-4-23-20(3-1)22(16-30-23)21-14-27-29-15-18(13-26-24(21)29)17-5-7-19(8-6-17)28-11-9-25-10-12-28/h1-8,13-16,25H,9-12H2
PDB
MMDB

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Article
PubMed
n/an/a 2.64E+3n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay

Bioorg Med Chem Lett 23: 3248-52 (2013)


Article DOI: 10.1016/j.bmcl.2013.03.113
BindingDB Entry DOI: 10.7270/Q2WW7K3P
More data for this
Ligand-Target Pair