BDBM50434758 CHEMBL2385585

SMILES: C1CN(CCO1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc2ccccc12

InChI Key: InChIKey=BRTTWVQRKMPQGY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bone morphogenetic protein 4 (Mus musculus)	BDBM50434758 (CHEMBL2385585) Show SMILES C1CN(CCO1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc2ccccc12 Show InChI InChI=1S/C24H20N4OS/c1-2-4-23-20(3-1)22(16-30-23)21-14-26-28-15-18(13-25-24(21)28)17-5-7-19(8-6-17)27-9-11-29-12-10-27/h1-8,13-16H,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	418	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 23: 3248-52 (2013) Article DOI: 10.1016/j.bmcl.2013.03.113 BindingDB Entry DOI: 10.7270/Q2WW7K3P
					More data for this Ligand-Target Pair