BDBM50434908 CHEMBL2385251

SMILES: CC(C(=O)NCc1ccc(nc1OCC1CCC(C)CC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=BPXLDPNUIDKFEV-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434908 (CHEMBL2385251) Show SMILES CC(C(=O)NCc1ccc(nc1OCC1CCC(C)CC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 |(52.24,-26.93,;52.24,-28.47,;50.91,-29.24,;50.91,-30.78,;49.57,-28.47,;48.24,-29.25,;46.91,-28.48,;46.9,-26.93,;45.57,-26.16,;44.24,-26.93,;44.23,-28.48,;45.57,-29.25,;45.57,-30.79,;46.91,-31.55,;46.91,-33.09,;45.58,-33.85,;45.58,-35.39,;46.92,-36.16,;46.92,-37.7,;48.25,-35.39,;48.25,-33.84,;42.9,-26.16,;42.9,-24.62,;41.57,-26.93,;41.56,-25.39,;53.58,-29.24,;53.57,-30.78,;54.9,-31.55,;56.24,-30.77,;57.57,-31.54,;58.9,-30.77,;60.24,-31.53,;58.12,-29.42,;59.66,-29.42,;56.23,-29.23,;57.56,-28.45,;54.9,-28.46,)| Show InChI InChI=1S/C25H31F4N3O4S/c1-15-4-6-17(7-5-15)14-36-24-19(9-11-22(31-24)25(27,28)29)13-30-23(33)16(2)18-8-10-21(20(26)12-18)32-37(3,34)35/h8-12,15-17,32H,4-7,13-14H2,1-3H3,(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of capsaicin-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434908 (CHEMBL2385251) Show SMILES CC(C(=O)NCc1ccc(nc1OCC1CCC(C)CC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 |(52.24,-26.93,;52.24,-28.47,;50.91,-29.24,;50.91,-30.78,;49.57,-28.47,;48.24,-29.25,;46.91,-28.48,;46.9,-26.93,;45.57,-26.16,;44.24,-26.93,;44.23,-28.48,;45.57,-29.25,;45.57,-30.79,;46.91,-31.55,;46.91,-33.09,;45.58,-33.85,;45.58,-35.39,;46.92,-36.16,;46.92,-37.7,;48.25,-35.39,;48.25,-33.84,;42.9,-26.16,;42.9,-24.62,;41.57,-26.93,;41.56,-25.39,;53.58,-29.24,;53.57,-30.78,;54.9,-31.55,;56.24,-30.77,;57.57,-31.54,;58.9,-30.77,;60.24,-31.53,;58.12,-29.42,;59.66,-29.42,;56.23,-29.23,;57.56,-28.45,;54.9,-28.46,)| Show InChI InChI=1S/C25H31F4N3O4S/c1-15-4-6-17(7-5-15)14-36-24-19(9-11-22(31-24)25(27,28)29)13-30-23(33)16(2)18-8-10-21(20(26)12-18)32-37(3,34)35/h8-12,15-17,32H,4-7,13-14H2,1-3H3,(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	6.0	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of pH 6 to 6.3-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair