BDBM50434957 CHEMBL2385233

SMILES: CC(C(=O)NCc1ccc(nc1OCc1cccc(F)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=OBXGYXWGYWCELN-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434957 (CHEMBL2385233) Show SMILES CC(C(=O)NCc1ccc(nc1OCc1cccc(F)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H22F5N3O4S/c1-14(16-6-8-20(19(26)11-16)32-37(2,34)35)22(33)30-12-17-7-9-21(24(27,28)29)31-23(17)36-13-15-4-3-5-18(25)10-15/h3-11,14,32H,12-13H2,1-2H3,(H,30,33)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of capsaicin-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434957 (CHEMBL2385233) Show SMILES CC(C(=O)NCc1ccc(nc1OCc1cccc(F)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H22F5N3O4S/c1-14(16-6-8-20(19(26)11-16)32-37(2,34)35)22(33)30-12-17-7-9-21(24(27,28)29)31-23(17)36-13-15-4-3-5-18(25)10-15/h3-11,14,32H,12-13H2,1-2H3,(H,30,33)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	6.0	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of pH 6 to 6.3-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair