BDBM50435181 CHEMBL2392935

SMILES: Cc1nc(nc(NCC(CCCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1

InChI Key: InChIKey=QJEVRTKPWCMUAX-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM50435181 (CHEMBL2392935) Show SMILES Cc1nc(nc(NCC(CCCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 Show InChI InChI=1S/C29H30Cl2N4/c1-21-27(31)29(35-28(34-21)26-18-17-25(30)20-32-26)33-19-24(23-14-8-4-9-15-23)16-10-3-7-13-22-11-5-2-6-12-22/h2,4-6,8-9,11-12,14-15,17-18,20,24H,3,7,10,13,16,19H2,1H3,(H,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Microtubule-associated protein 2 (Homo sapiens (Human))	BDBM50435181 (CHEMBL2392935) Show SMILES Cc1nc(nc(NCC(CCCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 Show InChI InChI=1S/C29H30Cl2N4/c1-21-27(31)29(35-28(34-21)26-18-17-25(30)20-32-26)33-19-24(23-14-8-4-9-15-23)16-10-3-7-13-22-11-5-2-6-12-22/h2,4-6,8-9,11-12,14-15,17-18,20,24H,3,7,10,13,16,19H2,1H3,(H,33,34,35)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair