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SMILES: Clc1ccc(CNc2nccc(n2)-c2ccc3OCOc3c2)cc1

InChI Key: InChIKey=FYRYKOQBRXRWER-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50435496 (CHEMBL2392363) Show SMILES Clc1ccc(CNc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C18H14ClN3O2/c19-14-4-1-12(2-5-14)10-21-18-20-8-7-15(22-18)13-3-6-16-17(9-13)24-11-23-16/h1-9H,10-11H2,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin) by bioluminescence assay				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Homo sapiens (Human))	BDBM50435496 (CHEMBL2392363) Show SMILES Clc1ccc(CNc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C18H14ClN3O2/c19-14-4-1-12(2-5-14)10-21-18-20-8-7-15(22-18)13-3-6-16-17(9-13)24-11-23-16/h1-9H,10-11H2,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of CLK4 (unknown origin) by bioluminescence assay				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair