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BDBM50435533 CHEMBL2392794

SMILES: Cc1cncn1CCCNC(=S)Nc1nccc2ccccc12

InChI Key: InChIKey=YEZNYDLKUAYTKM-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435533   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM50435533
PNG
(CHEMBL2392794)
Show SMILES Cc1cncn1CCCNC(=S)Nc1nccc2ccccc12
Show InChI InChI=1S/C17H19N5S/c1-13-11-18-12-22(13)10-4-8-20-17(23)21-16-15-6-3-2-5-14(15)7-9-19-16/h2-3,5-7,9,11-12H,4,8,10H2,1H3,(H2,19,20,21,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 158n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analys...


Bioorg Med Chem 21: 3821-30 (2013)


Article DOI: 10.1016/j.bmc.2013.04.005
BindingDB Entry DOI: 10.7270/Q2BR8TJF
More data for this
Ligand-Target Pair