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SMILES: COc1cc2c(Oc3ccc(NC(=O)c4cc(nc5ccccc45)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=HJPZKRAXGGLLCM-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435564   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50435564
PNG
(CHEMBL2392942)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4cc(nc5ccccc45)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C41H39FN4O4/c1-27-16-20-46(21-17-27)19-8-22-49-40-26-36-32(25-39(40)48-2)37(15-18-43-36)50-38-14-13-29(23-33(38)42)44-41(47)31-24-35(28-9-4-3-5-10-28)45-34-12-7-6-11-30(31)34/h3-7,9-15,18,23-27H,8,16-17,19-22H2,1-2H3,(H,44,47)
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KEGG

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PC cid
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Similars
Article
PubMed
n/an/a 2.70n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) after 30 mins by HTRF assay

Eur J Med Chem 64: 62-73 (2013)


Article DOI: 10.1016/j.ejmech.2013.04.001
BindingDB Entry DOI: 10.7270/Q27082SZ
More data for this
Ligand-Target Pair