Found 3 hits for monomerid = 50435575 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50435575
(CHEMBL2393135)Show SMILES FC(F)c1nc2c(OCCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C26H34F2N8O4/c27-22(28)23-29-21-19(3-1-4-20(21)40-12-2-5-33-6-13-37-14-7-33)36(23)26-31-24(34-8-15-38-16-9-34)30-25(32-26)35-10-17-39-18-11-35/h1,3-4,22H,2,5-18H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland
Curated by ChEMBL
| Assay Description Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr... |
Eur J Med Chem 64: 137-47 (2013)
Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50435575
(CHEMBL2393135)Show SMILES FC(F)c1nc2c(OCCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C26H34F2N8O4/c27-22(28)23-29-21-19(3-1-4-20(21)40-12-2-5-33-6-13-37-14-7-33)36(23)26-31-24(34-8-15-38-16-9-34)30-25(32-26)35-10-17-39-18-11-35/h1,3-4,22H,2,5-18H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland
Curated by ChEMBL
| Assay Description Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr... |
Eur J Med Chem 64: 137-47 (2013)
Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50435575
(CHEMBL2393135)Show SMILES FC(F)c1nc2c(OCCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C26H34F2N8O4/c27-22(28)23-29-21-19(3-1-4-20(21)40-12-2-5-33-6-13-37-14-7-33)36(23)26-31-24(34-8-15-38-16-9-34)30-25(32-26)35-10-17-39-18-11-35/h1,3-4,22H,2,5-18H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland
Curated by ChEMBL
| Assay Description Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra... |
Eur J Med Chem 64: 137-47 (2013)
Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 |
More data for this Ligand-Target Pair | |