Found 3 hits for monomerid = 50435584 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50435584
(CHEMBL2393146)Show SMILES OC(=O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C21H23F2N7O5/c22-17(23)18-24-16-13(2-1-3-14(16)35-12-15(31)32)30(18)21-26-19(28-4-8-33-9-5-28)25-20(27-21)29-6-10-34-11-7-29/h1-3,17H,4-12H2,(H,31,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland
Curated by ChEMBL
| Assay Description Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr... |
Eur J Med Chem 64: 137-47 (2013)
Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50435584
(CHEMBL2393146)Show SMILES OC(=O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C21H23F2N7O5/c22-17(23)18-24-16-13(2-1-3-14(16)35-12-15(31)32)30(18)21-26-19(28-4-8-33-9-5-28)25-20(27-21)29-6-10-34-11-7-29/h1-3,17H,4-12H2,(H,31,32) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland
Curated by ChEMBL
| Assay Description Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr... |
Eur J Med Chem 64: 137-47 (2013)
Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50435584
(CHEMBL2393146)Show SMILES OC(=O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C21H23F2N7O5/c22-17(23)18-24-16-13(2-1-3-14(16)35-12-15(31)32)30(18)21-26-19(28-4-8-33-9-5-28)25-20(27-21)29-6-10-34-11-7-29/h1-3,17H,4-12H2,(H,31,32) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 274 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland
Curated by ChEMBL
| Assay Description Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra... |
Eur J Med Chem 64: 137-47 (2013)
Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 |
More data for this Ligand-Target Pair | |