BDBM50435926 CHEMBL2391266

SMILES: COc1ccc(cc1)-c1cc(Cc2cccc(OC)c2)c(=O)n(CC(=O)Nc2ccc(F)cc2)n1

InChI Key: InChIKey=QNEIUZOSVVSZRQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
FML2_HUMAN (Homo sapiens (Human))	BDBM50435926 (CHEMBL2391266) Show SMILES COc1ccc(cc1)-c1cc(Cc2cccc(OC)c2)c(=O)n(CC(=O)Nc2ccc(F)cc2)n1 Show InChI InChI=1S/C27H24FN3O4/c1-34-23-12-6-19(7-13-23)25-16-20(14-18-4-3-5-24(15-18)35-2)27(33)31(30-25)17-26(32)29-22-10-8-21(28)9-11-22/h3-13,15-16H,14,17H2,1-2H3,(H,29,32)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Agonist activity at FPR3 (unknown origin) transfected in human HL60 cells assessed as induction of Ca2+ mobilization				Eur J Med Chem 64: 512-28 (2013) Article DOI: 10.1016/j.ejmech.2013.03.066 BindingDB Entry DOI: 10.7270/Q2N29ZBP
					More data for this Ligand-Target Pair