BDBM50436229 CHEMBL2398685

SMILES: CSc1cccc(c1)C(=O)N1CCCC(C1)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=GWOYPRVQVUHBBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transforming protein RhoA (Homo sapiens (Human))	BDBM50436229 (CHEMBL2398685) Show SMILES CSc1cccc(c1)C(=O)N1CCCC(C1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C20H21ClN2O2S/c1-26-18-6-2-4-14(12-18)20(25)23-11-3-5-15(13-23)19(24)22-17-9-7-16(21)8-10-17/h2,4,6-10,12,15H,3,5,11,13H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of RhoC-mediated pathway in human PC3 cells assessed as inhibition of SRE-regulated gene transcription by luciferase reporter gene assay				Bioorg Med Chem Lett 23: 3826-32 (2013) Article DOI: 10.1016/j.bmcl.2013.04.080 BindingDB Entry DOI: 10.7270/Q28P61XS
					More data for this Ligand-Target Pair