BDBM50436374 CHEMBL2396726
SMILES: OC(=O)COc1ccc(cc1)-c1oc2cc(O)c(cc2c1C#Cc1cccc(Cl)c1)C(O)=O
InChI Key: InChIKey=MVXDJODNTDKLTA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human)) | BDBM50436374 (CHEMBL2396726) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat... | J Med Chem 56: 4990-5008 (2013) Article DOI: 10.1021/jm400248c BindingDB Entry DOI: 10.7270/Q2N017XW | |||||||||||
More data for this Ligand-Target Pair |