BDBM50436631 CHEMBL2398280

SMILES: CC(N=Nc1ccc2ccccc2n1)c1ccc(o1)-c1cccc(C(O)=O)c1Cl

InChI Key: InChIKey=APPXRKOCTBCFNE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50436631 (CHEMBL2398280) Show SMILES CC(N=Nc1ccc2ccccc2n1)c1ccc(o1)-c1cccc(C(O)=O)c1Cl |w:3.3| Show InChI InChI=1S/C22H16ClN3O3/c1-13(25-26-20-12-9-14-5-2-3-8-17(14)24-20)18-10-11-19(29-18)15-6-4-7-16(21(15)23)22(27)28/h2-13H,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute of Medical Research Curated by ChEMBL					Assay Description Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assay				J Med Chem 56: 5514-40 (2014) Article DOI: 10.1021/jm400556w BindingDB Entry DOI: 10.7270/Q2X92CQT
					More data for this Ligand-Target Pair