BDBM50437016 CHEMBL2402907

SMILES: CCNC(=O)C(C1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2ccsc2)cc1F)c1ccccc1

InChI Key: InChIKey=RIGQMJQWXWAARJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50437016 (CHEMBL2402907) Show SMILES CCNC(=O)C(C1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2ccsc2)cc1F)c1ccccc1 Show InChI InChI=1S/C32H32FN3O2S/c1-2-34-32(38)30(22-8-4-3-5-9-22)23-14-17-36(18-15-23)29-13-12-25(20-28(29)33)35-31(37)27-11-7-6-10-26(27)24-16-19-39-21-24/h3-13,16,19-21,23,30H,2,14-15,17-18H2,1H3,(H,34,38)(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...				Bioorg Med Chem Lett 23: 4141-4 (2013) Article DOI: 10.1016/j.bmcl.2013.05.038 BindingDB Entry DOI: 10.7270/Q29C6ZV8
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50437016 (CHEMBL2402907) Show SMILES CCNC(=O)C(C1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2ccsc2)cc1F)c1ccccc1 Show InChI InChI=1S/C32H32FN3O2S/c1-2-34-32(38)30(22-8-4-3-5-9-22)23-14-17-36(18-15-23)29-13-12-25(20-28(29)33)35-31(37)27-11-7-6-10-26(27)24-16-19-39-21-24/h3-13,16,19-21,23,30H,2,14-15,17-18H2,1H3,(H,34,38)(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development LLC Curated by ChEMBL					Assay Description Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysis				Bioorg Med Chem Lett 23: 4141-4 (2013) Article DOI: 10.1016/j.bmcl.2013.05.038 BindingDB Entry DOI: 10.7270/Q29C6ZV8
					More data for this Ligand-Target Pair