BDBM50437174 CHEMBL2401828

SMILES: C[C@@H](Oc1c(N)ncc2c(coc12)C1=CCN(CC1)C(C)=O)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=JHXOYBYPYLVIMP-LLVKDONJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50437174 (CHEMBL2401828) Show SMILES C[C@@H](Oc1c(N)ncc2c(coc12)C1=CCN(CC1)C(C)=O)c1c(Cl)ccc(F)c1Cl |r,t:15| Show InChI InChI=1S/C22H20Cl2FN3O3/c1-11(18-16(23)3-4-17(25)19(18)24)31-21-20-14(9-27-22(21)26)15(10-30-20)13-5-7-28(8-6-13)12(2)29/h3-5,9-11H,6-8H2,1-2H3,(H2,26,27)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, LLC Curated by ChEMBL					Assay Description Inhibition of cMET (unknown origin) using biotinylated poly(Glu,Tyr) as substrate after 60 mins				Bioorg Med Chem Lett 23: 4381-7 (2013) Article DOI: 10.1016/j.bmcl.2013.05.074 BindingDB Entry DOI: 10.7270/Q2RB7601
					More data for this Ligand-Target Pair